The grandaddy of the Industry continues to set the pace for scalable operations. More than any of the other large players, the company has taken criticisms of "lack of objectivity" to heart and spread its operations throughout a series of very useful alliances. By sticking with a cleanly evolved front end and tweaking it slowly, the CM sets a standard for usability over time.
Preferring to keep its "light under a basket", CM's simple front end hides an extraordinary wealth of services and targeting. The backroom team responsible for ongoing design is extremely good at weaving the latest accomplishment seamlessly into the existing structure.